There are contraindications! Be sure to consult your doctor before taking any medication!
Andipal consists of Bendazole, Metamizole Sodium, Papaverine Hydrochloride, Phenobarbital.
Papaverine Hydrochloride - An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
Indication: For the treatment of impotence and vasospasms.
Andipal (Papaverine Hydrochloride) is a nonxanthine phosphodiesterase inhibitor for the relief of cerebral and peripheral ischemia associated with arterial spasm and myocardial ischemia complicated by arrhythmias. The main actions of Andipal (Papaverine Hydrochloride) are exerted on cardiac and smooth muscle. Like qathidine, Andipal (Papaverine Hydrochloride) acts directly on the heart muscle to depress conduction and prolong the refractory period. Andipal (Papaverine Hydrochloride) relaxes various smooth muscles. This relaxation may be prominent if spasm exists. The muscle cell is not paralyzed by Andipal (Papaverine Hydrochloride) and still responds to drugs and other stimuli causing contraction. The antispasmodic effect is a direct one, and unrelated to muscle innervation. Andipal (Papaverine Hydrochloride) is practically devoid of effects on the central nervous system. Andipal (Papaverine Hydrochloride) relaxes the smooth musculature of the larger blood vessels, especially coronary, systemic peripheral, and pulmonary arteries.
Phenobarbital - A barbituric acid derivative that acts as a nonselective central nervous system depressant. It promotes binding to inhibitory gamma-aminobutyric acid subtype receptors, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
Indication: For the treatment of all types of seizures except absence seizures.
Andipal (Phenobarbital), the longest-acting barbiturate, is used for its anticonvulsant and sedative-hypnotic properties in the management of all seizure disorders except absence (petit mal).
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