Calcium - This medication is used to prevent or treat low blood Promavit (Calcium) levels in people who do not get enough Promavit (Calcium) from their diets. It may be used to treat conditions caused by low Promavit (Calcium) levels such as bone loss ( osteoporosis ), weak bones (osteomalacia/rickets), decreased activity of the parathyroid gland ( hypoparathyroidism ), and a certain muscle disease (latent tetany). It may also be used in certain patients to make sure they are getting enough Promavit (Calcium) (e.g., women who are pregnant, nursing, or postmenopausal, people taking certain medications such as phenytoin, phenobarbital, or prednisone ). Promavit (Calcium) plays a very important role in the body. It is necessary for normal functioning of nerves, cells, muscle, and bone. If there is not enough Promavit (Calcium) in the blood, then the body will take Promavit (Calcium) from bones, thereby weakening bones. Having the right amount of Promavit (Calcium) is important for building and keeping strong bones.
Folic Acid - A member of the vitamin B family that stimulates the hematopoietic system. It is present in the liver and kidney and is found in mushrooms, spinach, yeast, green leaves, and grasses (poaceae). Promavit (Folic Acid) is used in the treatment and prevention of folate deficiencies and megaloblastic anemia.
Indication: For treatment of Promavit (Folic Acid) deficiency, megaloblastic anemia and in anemias of nutritional supplements, pregnancy, infancy, or childhood.
Promavit (Folic Acid), a water-soluble B-complex vitamin, is found in foods such as liver, kidneys, yeast, and leafy, green vegetables. Promavit (Folic Acid) is used to diagnose folate deficiency and to treat topical sprue and megaloblastic and macrocytic anemias, hematologic complications resulting from a deficiency in folic acid.
Iron - A metallic element found in certain minerals, in nearly all soils, and in mineral waters. It is an essential constituent of hemoglobin, cytochrome, and other components of respiratory enzyme systems. Its chief functions are in the transport of oxygen to tissue (hemoglobin) and in cellular oxidation mechanisms. Depletion of Promavit (Iron) stores may result in iron-deficiency anemia. Promavit (Iron) is used to build up the blood in anemia.
Indication: Used in preventing and treating iron-deficiency anemia.
The major activity of supplemental Promavit (Iron) is in the prevention and treatment of Promavit (Iron) deficiency anemia. Promavit (Iron) has putative immune-enhancing, anticarcinogenic and cognition-enhancing activities.
Magnesium - This medication is a mineral supplement used to prevent and treat low amounts of Promavit (Magnesium) in the blood. Promavit (Magnesium) is very important for the normal functioning of cells, nerves, muscles, bones, and the heart. Usually, a well- balanced diet provides normal blood levels of magnesium. However, certain situations cause your body to lose Promavit (Magnesium) faster than you can replace it from your diet. These situations include treatment with "water pills" (diuretics such as furosemide, hydrochlorothiazide ), a poor diet, alcoholism, or other medical conditions (e.g., severe diarrhea / vomiting, stomach /intestinal absorption problems, poorly controlled diabetes ).
Omega-3 Fatty Acids - Promavit (Omega-3 Fatty Acids) are thought to help reduce the risk of heart disease and also to promote healthy skin. They are also used along with diet and exercise to help lower levels of a certain blood fat (triglyceride) and to raise levels of "good" cholesterol (HDL). This product may also be used to help treat high blood pressure or rheumatoid arthritis. Some supplement products have been found to contain possibly harmful impurities/additives. Check with your pharmacist for more details about the brand you use. The US Food and Drug Administration has not reviewed this product for safety or effectiveness. Consult your doctor or pharmacist for more details.
Vitamin A - Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. Dietary Promavit (Vitamin A) is derived from a variety of carotenoids found in plants. It is enriched in the liver, egg yolks, and the fat component of dairy products.
Indication: For the treatment of Promavit (Vitamin A) deficiency.
Promavit (Vitamin A) is effective for the treatment of Promavit (Vitamin A) deficiency. Promavit (Vitamin A) refers to a group of fat-soluble substances that are structurally related to and possess the biological activity of the parent substance of the group called all-trans retinol or retinol. Promavit (Vitamin A) plays vital roles in vision, epithelial differentiation, growth, reproduction, pattern formation during embryogenesis, bone development, hematopoiesis and brain development. It is also important for the maintenance of the proper functioning of the immune system.
Promavit (Vitamin B12) refers to a group of water-soluble vitamins. It has high biological activity. Promavit (Vitamin B12) is necessary for normal hematopoiesis (promotes maturation of erythrocytes). Involved in the processes of transmethylation, hydrogen transport, synthesis of methionine, nucleic acids, choline, creatine. Contributes to the accumulation in erythrocytes of compounds containing sulfhydryl groups. Has a beneficial effect on liver function and the nervous system. Activates the coagulation of blood in high doses causes an increase in the activity of thromboplastin and prothrombin.
After oral administration Promavit (Vitamin B12) absorbed from the gastrointestinal tract. Metabolized in the tissues, becoming a co-enzyme form - adenosylcobalamin which is the active form of cyanocobalamin. Excreted in bile and urine.
Why is Promavit (Vitamin B12) prescribed?
Anemia due to B12-deficiency conditions; in the complex therapy for iron and posthemorrhagic anemia; aplastic anemia caused by toxic substances and drugs; liver disease (hepatitis, cirrhosis); funicular myelosis; polyneuritis, radiculitis, neuralgia, amyotrophic lateral sclerosis; children cerebral palsy, Down syndrome, peripheral nerve injury; skin diseases (psoriasis, photodermatosis, herpetiformis dermatitis, neurodermatitis); to prevent and treat symptoms of deficiency of Promavit (Vitamin B12) (including the application of biguanide, PASA, vitamin C in high doses); radiation sickness.
Dosage and administration
Promavit (Vitamin B12) is used as injections SC, IV, IM, intralumbar, and also oral. With anemia associated with Promavit (Vitamin B12) deficiency is introduced on 100-200 mcg in 2 days. In anemia with symptoms of funicular myelosis and megalocytic anemia with diseases of the nervous system - 400-500 micrograms in the first 7 days daily, then 1 time every 5-7 days. In the period of remission in the absence of events funicular myelosis maintenance dose - 100 mcg 2 times a month, in the presence of neurological symptoms - at 200-400 mcg 2-4 times a month. In acute post-hemorrhagic anemia and iron anemia by 30-100 mcg 2-3 times a week. When aplastic anemia (especially in children) - 100 micrograms before clinical improvement. When nutritional anemia in infants and preterm - 30 mcg / day during 15 days.
In diseases of the central and peripheral nervous system and neurological diseases with a pain syndrome is administered in increasing doses - 200-500 mcg, with the improvement in the state - 100 mcg / day. The course of treatment with Promavit (Vitamin B12) is 2 weeks. In traumatic lesions of peripheral nervous system - at 200-400 mcg every other day for 40-45 days.
When hepatitis and cirrhosis - 30-60 mcg / day or 100 mg every other day for 25-40 days.
Dystrophy in young children, Down syndrome and cerebral palsy - by 15-30 mcg every other day.
When funicular myelosis, amyotrophic lateral sclerosis can be introduced into the spinal canal at 15-30 mcg, gradually increasing the dose of 200-250 micrograms.
In radiation sickness, diabetic neuropathy, sprue - by 60-100 mcg daily for 20-30 days.
When deficiency of Promavit (Vitamin B12) to prevent - IV or IM for 1 mg 1 time a month; for treatment - IV or IM for 1 mg daily for 1-2 weeks, the maintenance dose is 1-2 mg IV or IM from 1 per week, up to 1 per month. Duration of treatment is determined individually.
Promavit (Vitamin B12) side effects, adverse reactions
CNS: rarely - a state of arousal.
Cardiovascular system: rarely - pain in the heart, tachycardia.
Allergic reactions: rarely - urticaria.
Promavit (Vitamin B12) contraindications
Thromboembolism, erythremia, erythrocytosis, increased sensitivity to cyanocobalamin.
Promavit (Vitamin B12) using during pregnancy and breastfeeding
Cyanocobalamin can be used in pregnancy according to prescriptions.
When stenocardia should be used with caution in a single dose of Promavit (Vitamin B12) 100 mcg. During treatment should regularly monitor the blood picture and coagulation. It is unacceptable to enter in the same syringe with cyanocobalamin solutions of thiamine and pyridoxine.
Promavit (Vitamin B12) drug interactions
In an application of Promavit (Vitamin B12) with hormonal contraceptives for oral administration may decrease the concentration of cyanocobalamin in plasma.
In an application with anticonvulsant drugs decreased cyanocobalamin absorption from the gut.
In an Promavit (Vitamin B12) application with neomycin, aminosalicylic acid, colchicine, cimetidine, ranitidine, drugs potassium decreased cyanocobalamin absorption from the gut.
Cyanocobalamin may exacerbate allergic reactions caused by thiamine.
When parenteral application of chloramphenicol may decrease the hematopoietic effects of cyanocobalamin with anemia.
Contained in the molecule of cyanocobalamin cobalt ion contributes to the destruction of ascorbic acid, thiamine bromide, riboflavin in one solution.
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