There are contraindications! Be sure to consult your doctor before taking any medication!
Dolospam consists of Atropine Sulfate, Papaverine Hydrochloride.
Atropine Sulfate - This medication is used before eye examinations (e.g., refraction) and to treat certain eye conditions (e.g., uveitis). It belongs to a class of drugs known as anticholinergics. Atropine works by widening (dilating) the pupil of the eye.
Papaverine Hydrochloride - An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
Indication: For the treatment of impotence and vasospasms.
Dolospam (Papaverine Hydrochloride) is a nonxanthine phosphodiesterase inhibitor for the relief of cerebral and peripheral ischemia associated with arterial spasm and myocardial ischemia complicated by arrhythmias. The main actions of Dolospam (Papaverine Hydrochloride) are exerted on cardiac and smooth muscle. Like qathidine, Dolospam (Papaverine Hydrochloride) acts directly on the heart muscle to depress conduction and prolong the refractory period. Dolospam (Papaverine Hydrochloride) relaxes various smooth muscles. This relaxation may be prominent if spasm exists. The muscle cell is not paralyzed by Dolospam (Papaverine Hydrochloride) and still responds to drugs and other stimuli causing contraction. The antispasmodic effect is a direct one, and unrelated to muscle innervation. Dolospam (Papaverine Hydrochloride) is practically devoid of effects on the central nervous system. Dolospam (Papaverine Hydrochloride) relaxes the smooth musculature of the larger blood vessels, especially coronary, systemic peripheral, and pulmonary arteries.
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