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Ions of sodium and chlorine are the major inorganic components of the extracellular fluid, maintaining an appropriate osmotic pressure of blood plasma and extracellular fluid. Isotonic solution of Narium fills a deficit of body fluids during dehydration. Hypertonic solution of Narium for IV injection provides a correction of osmotic pressure of extracellular fluid and blood plasma. When applied topically in ophthalmology Narium has anti-edema effect.
Why is Narium prescribed?
Narium as isotonic solution: the dehydration of various origins. To maintain the volume of blood plasma during and after surgery. As a solvent for various drugs.
Hypertonic solution: violations of water-electrolyte metabolism: lack of sodium and chlorine ions; hypoosmotic dehydration of various origins (due to prolonged vomiting, diarrhea, burns with a gastric fistula, pulmonary hemorrhage, intestinal bleeding).
Eye drops and ointment: irritation of the cornea with inflammatory and allergic diseases (combined therapy).
Dosage and administration
Isotonic Narium solution used as injected iv, sc, and enemas and is also used for washing wounds, eyes, mucous nasal cavity. Often administered as IV depending on the clinical situation up to 3 L / day.
Hypertonic Narium solution injected intravenous. Single dose for IV jet injection can be 10-30 ml. For conditions requiring immediate replenishment of sodium and chloride ions Narium is administered as IV infusion at a dose of 100 ml.
Locally and externally applied depending on the dosage form and regimen.
For external and local application adverse reactions to this date have not been established.
Hypernatremia, hyperhydration, the threat of pulmonary edema, cerebral edema.
With careful use of large amounts of Narium in patients with impaired renal excretory function and hypokalemia. The injection of large amounts of solution can lead to chloride acidosis, hyperhydration, increased excretion of potassium from the body.
Hypertonic solution of Narium do not applied SC and IM.
With prolonged use is necessary to monitor the concentration of electrolytes in the plasma and the daily urine output.
The temperature of infusion solution should be 38 °C.
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